FIGURE 5.

Change in maximal enzymatic activity and protein content in muscle samples after 6 weeks of twice-daily inhalation of formoterol (48 µg·day⁻¹) in endurance-trained males (n=11) and females (n=10) versus placebo (males n=10, females n=10). Pooled data from males and females are shown (all). a) Maximal activity of mitochondrial enzymes citrate synthase (CS) and hydroxyacyl-CoA dehydrogenase (HAD); b) muscle protein content of HAD and platelet endothelial cell adhesion molecule-1 (PECAM-1); c) muscle protein content of mitochondrial complexes I–V (CI–V). Values are effect sizes compared with placebo with 95% confidence intervals. a.u.: arbitrary units. *: p<0.05 (different from placebo within-sex); ^#: p<0.05 (treatment×trial interaction effect).