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Mean (±SEM) changes in NAc and SC oxygen levels induced by iv injection of fentanyl (20 μg/kg) in awake, freely moving rats. A. = changes averaged with 1-min quantification bin for 60 min post-injection; B. = changes averaged with 10-s quantification bin for 10 min post-injection; C. = Correlative relationships between oxygen changes in the NAc and SC space. Filled symbols show values significantly different (p<0.05) from the last pre-injection value. r = coefficient of correlation.
