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. 2023 Mar 25;30(2):92–109. doi: 10.3390/pathophysiology30020009

Table 2.

Results of univariate analysis.

Factors Total Univariate Analysis
HR 95% CI p−Value
Gender
Male 19 1.72 0.74–4.03 0.210
Female 15 1
Age
≥60 11 0.85 0.35–2.09 0.731
<60 23 1
Grade
>1 20 1.55 0.66–3.65 0.311
1 14 1
Perineural invasion
Present 11 1.02 0.42–2.50 0.959
Not Present 23 1
Lymphovascular invasion
Present 6 0.50 0.15–1.70 0.268
Not Present 28 1
Type of specimen
Biopsy 13 1.49 0.65–3.41 0.341
Resection 21 1
Cancer stage
III–IV 24 1.82 0.60–5.55 0.289
I–II 10 1
NF−κB (RelA) cytoplasmic status
Positive 14 0.37 0.14–1.03 0.058
Negative 20 1
NF−κB (RelA) nuclear status
Positive 11 0.29 0.10–0.84 0.022 *
Negative 23 1
COX−2 status
Positive 28 0.67 0.19–2.35 0.531
Negative 6 1
Sp1 status
Positive 19 0.91 0.39–2.12 0.830
Negative 15 1
c−Jun status
Positive 15 0.90 0.39–2.06 0.799
Negative 19 1
Co−expressions of NF−κB (nuclear), COX−2, Sp1, c−Jun
Yes 6 0.43 0.14–1.29 0.133
No 28 1
Gender

Abbreviations: COX−2 = cyclooxygenase−2; NF−κB = nuclear factor kappa−B; Sp1 = specificity protein 1; HR = hazard ratio; and 95% CI = 95% confidence interval. * p < 0.05.