Table 2.
Factors | Total | Univariate Analysis | ||
---|---|---|---|---|
HR | 95% CI | p−Value | ||
Gender | ||||
Male | 19 | 1.72 | 0.74–4.03 | 0.210 |
Female | 15 | 1 | ||
Age | ||||
≥60 | 11 | 0.85 | 0.35–2.09 | 0.731 |
<60 | 23 | 1 | ||
Grade | ||||
>1 | 20 | 1.55 | 0.66–3.65 | 0.311 |
1 | 14 | 1 | ||
Perineural invasion | ||||
Present | 11 | 1.02 | 0.42–2.50 | 0.959 |
Not Present | 23 | 1 | ||
Lymphovascular invasion | ||||
Present | 6 | 0.50 | 0.15–1.70 | 0.268 |
Not Present | 28 | 1 | ||
Type of specimen | ||||
Biopsy | 13 | 1.49 | 0.65–3.41 | 0.341 |
Resection | 21 | 1 | ||
Cancer stage | ||||
III–IV | 24 | 1.82 | 0.60–5.55 | 0.289 |
I–II | 10 | 1 | ||
NF−κB (RelA) cytoplasmic status | ||||
Positive | 14 | 0.37 | 0.14–1.03 | 0.058 |
Negative | 20 | 1 | ||
NF−κB (RelA) nuclear status | ||||
Positive | 11 | 0.29 | 0.10–0.84 | 0.022 * |
Negative | 23 | 1 | ||
COX−2 status | ||||
Positive | 28 | 0.67 | 0.19–2.35 | 0.531 |
Negative | 6 | 1 | ||
Sp1 status | ||||
Positive | 19 | 0.91 | 0.39–2.12 | 0.830 |
Negative | 15 | 1 | ||
c−Jun status | ||||
Positive | 15 | 0.90 | 0.39–2.06 | 0.799 |
Negative | 19 | 1 | ||
Co−expressions of NF−κB (nuclear), COX−2, Sp1, c−Jun | ||||
Yes | 6 | 0.43 | 0.14–1.29 | 0.133 |
No | 28 | 1 | ||
Gender |
Abbreviations: COX−2 = cyclooxygenase−2; NF−κB = nuclear factor kappa−B; Sp1 = specificity protein 1; HR = hazard ratio; and 95% CI = 95% confidence interval. * p < 0.05.