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. 2023 Apr 6;11(2):58. doi: 10.3390/diseases11020058

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Nanocarrier drug conjugates showed significant amoebicidal effects against Balamuthia mandrillaris and Naegleria fowleri. Significant antiamoebic effects of the majority of compounds against B. mandrillaris (a) and N. fowleri (b) were observed after a 24 h incubation period. All data is illustrative as the mean ± standard error. Additionally, p-values were determined through the conduction of a two sample t-test, (*) is ≤ 0.05. AMPB is Amphotericin B; LEC is Lecithin; LBA is lactobionic acid; CUR is curcumin; MNP is magnetic nanoparticles.