Skip to main content
. Author manuscript; available in PMC: 2023 Apr 24.
Published in final edited form as: Am J Psychiatry. 2022 Dec 7;180(1):23–40. doi: 10.1176/appi.ajp.21100992

Figure 1. Overview of database search.

Figure 1.

A) 5,799 independent records were identified from searches of Medline, Embase, and Scopus. Applying seven inclusion criteria in three steps yielded 248 articles, with an additional 32 included from citations giving a final review set of 280 articles. B) At each step of the application of inclusion criteria the overlap between the three databases is shown by Venn diagrams. C-D) The number of records that met or did not meet combinations of the first three criteria (C) or fifth to seventh criteria (D) is shown in these upset plots. A complete record of this process is recorded in Table S1. E) The 280 articles are subdivided by experimental design. F) Types of biomarker assessed in each of the five types of experimental design.