Table 1.
GO, KEGG and BIOCARTA analysis based on DAVID. (Up-DEGs between DMSO with CIS)
| GO | Category | Count | -Log2(P Value) | |
|---|---|---|---|---|
| GOTERM_BP_DIRECT | GO:0006334 ~ nucleosome assembly | 22 | 42.403049 | |
| GOTERM_BP_DIRECT | GO:0006335 ~ DNA replication-dependent nucleosome assembly | 11 | 27.74878128 | |
| GOTERM_BP_DIRECT | GO:0043065 ~ positive regulation of apoptotic process | 29 | 21.32817221 | |
| GOTERM_BP_DIRECT | GO:0060968 ~ regulation of gene silencing | 6 | 16.60892704 | |
| GOTERM_BP_DIRECT | GO:0008285 ~ negative regulation of cell proliferation | 28 | 16.45457063 | |
| GOTERM_BP_DIRECT | GO:0006954 ~ inflammatory response | 26 | 15.93301132 | |
| GOTERM_BP_DIRECT | GO:0000786 ~ nucleosome | 24 | 40.02493217 | |
| GOTERM_BP_DIRECT | GO:0005576 ~ extracellular region | 87 | 27.93206549 | |
| GOTERM_BP_DIRECT | GO:0005615 ~ extracellular space | 85 | 22.10672588 | |
| GOTERM_BP_DIRECT | GO:0000228 ~ nuclear chromosome | 11 | 20.94169347 | |
| GOTERM_CC_DIRECT | GO:0001533 ~ cornified envelope | 10 | 15.2297727 | |
| GOTERM_CC_DIRECT | GO:0016020 ~ membrane | 204 | 12.79847186 | |
| GOTERM_CC_DIRECT | GO:0005125 ~ cytokine activity | 23 | 22.05968309 | |
| GOTERM_CC_DIRECT | GO:0008083 ~ growth factor activity | 17 | 18.742172 | |
| GOTERM_CC_DIRECT | GO:0030527 ~ structural constituent of chromatin | 5 | 15.99923777 | |
| GOTERM_CC_DIRECT | GO:0,046,982 ~ protein heterodimerization activity | 25 | 13.51717047 | |
| GOTERM_CC_DIRECT | GO:0008330 ~ protein tyrosine/threonine phosphatase activity | 5 | 12.88292008 | |
| GOTERM_CC_DIRECT | GO:0017017 ~ MAP kinase tyrosine/serine/threonine phosphatase activity | 5 | 11.8276452 | |
| GOTERM_CC_DIRECT | mmu05322:Systemic lupus erythematosus | 21 | 28.48228567 | |
| GOTERM_CC_DIRECT | mmu05034:Alcoholism | 22 | 22.65126955 | |
| GOTERM_MF_DIRECT | mmu04613:Neutrophil extracellular trap formation | 22 | 22.41079607 | |
| GOTERM_MF_DIRECT | mmu05202:Transcriptional misregulation in cancer | 20 | 16.57777767 | |
| GOTERM_MF_DIRECT | mmu04668:TNF signaling pathway | 14 | 16.49493421 | |
| GOTERM_MF_DIRECT | mmu04657:IL-17 signaling pathway | 12 | 14.60610374 | |
| GOTERM_MF_DIRECT | m_stemPathway:Regulation of hematopoiesis by cytokines | 6 | 11.73475312 | |
| GOTERM_MF_DIRECT | m_erythPathway:Erythrocyte Differentiation Pathway | 6 | 11.2031028 | |
| GOTERM_MF_DIRECT | m_dspPathway:Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases | 5 | 11.01320069 | |
| GOTERM_MF_DIRECT | m_atmPathway:ATM Signaling Pathway | 5 | 6.317244644 | |
| GOTERM_MF_DIRECT | m_ngfPathway:Nerve growth factor pathway (NGF) | 5 | 5.6012101 | |
| GOTERM_MF_DIRECT | GO:0006334 ~ nucleosome assembly | 22 | 42.403049 | |
| KEGG_PATHWAY | GO:0006335 ~ DNA replication-dependent nucleosome assembly | 11 | 27.74878128 | |
| KEGG_PATHWAY | GO:0043065 ~ positive regulation of apoptotic process | 29 | 21.32817221 | |
| KEGG_PATHWAY | GO:0060968 ~ regulation of gene silencing | 6 | 16.60892704 | |
| KEGG_PATHWAY | GO:0008285 ~ negative regulation of cell proliferation | 28 | 16.45457063 | |
| KEGG_PATHWAY | GO:0006954 ~ inflammatory response | 26 | 15.93301132 | |
| KEGG_PATHWAY | GO:0000786 ~ nucleosome | 24 | 40.02493217 | |
| KEGG_PATHWAY | GO:0005576 ~ extracellular region | 87 | 27.93206549 | |
| KEGG_PATHWAY | GO:0005615 ~ extracellular space | 85 | 22.10672588 | |
| KEGG_PATHWAY | GO:0000228 ~ nuclear chromosome | 11 | 20.94169347 | |
| KEGG_PATHWAY | GO:0001533 ~ cornified envelope | 10 | 15.2297727 | |
| BIOCARTA | GO:0016020 ~ membrane | 204 | 12.79847186 | |
| BIOCARTA | GO:0005125 ~ cytokine activity | 23 | 22.05968309 | |
| BIOCARTA | GO:0008083 ~ growth factor activity | 17 | 18.742172 | |
| BIOCARTA | GO:0030527 ~ structural constituent of chromatin | 5 | 15.99923777 | |
| BIOCARTA | GO:0046982 ~ protein heterodimerization activity | 25 | 13.51717047 | |
| BIOCARTA | GO:0008330 ~ protein tyrosine/threonine phosphatase activity | 5 | 12.88292008 | |
| BIOCARTA | GO:0017017 ~ MAP kinase tyrosine/serine/threonine phosphatase activity | 5 | 11.8276452 |