Table 2.
GO, KEGG and BIOCARTA analysis based on DAVID. (Down-DEGs between DMSO with CIS)
| GO | Category | Count | -Log2(P Value) |
|---|---|---|---|
| GOTERM_BP_DIRECT | GO:0030010 ~ establishment of cell polarity | 6 | 4.84265555 |
| GOTERM_BP_DIRECT | GO:0007420 ~ brain development | 10 | 9.291692541 |
| GOTERM_BP_DIRECT | GO:0030198 ~ extracellular matrix organization | 8 | 8.723977207 |
| GOTERM_BP_DIRECT | GO:0007399 ~ nervous system development | 12 | 7.879202652 |
| GOTERM_BP_DIRECT | GO:0007030 ~ Golgi organization | 6 | 7.848307704 |
| GOTERM_BP_DIRECT | GO:0015031 ~ protein transport | 15 | 7.756581427 |
| GOTERM_BP_DIRECT | GO:0016020 ~ membrane | 100 | 17.7794164 |
| GOTERM_BP_DIRECT | GO:0005737 ~ cytoplasm | 105 | 16.41697626 |
| GOTERM_BP_DIRECT | GO:0005794 ~ Golgi apparatus | 31 | 13.40458113 |
| GOTERM_BP_DIRECT | GO:0030315 ~ T-tubule | 6 | 11.00613272 |
| GOTERM_CC_DIRECT | GO:0043005 ~ neuron projection | 15 | 8.74749388 |
| GOTERM_CC_DIRECT | GO:0005856 ~ cytoskeleton | 26 | 8.386444372 |
| GOTERM_CC_DIRECT | GO:0000166 ~ nucleotide binding | 33 | 11.0905486 |
| GOTERM_CC_DIRECT | GO:0035091 ~ phosphatidylinositol binding | 6 | 7.733881177 |
| GOTERM_CC_DIRECT | GO:0005524 ~ ATP binding | 27 | 7.467695552 |
| GOTERM_CC_DIRECT | GO:0005085 ~ guanyl-nucleotide exchange factor activity | 8 | 7.030604737 |
| GOTERM_CC_DIRECT | GO:0051015 ~ actin filament binding | 8 | 6.842845867 |
| GOTERM_CC_DIRECT | GO:0004698 ~ calcium-dependent protein kinase C activity | 3 | 6.508653954 |
| GOTERM_CC_DIRECT | mmu04015:Rap1 signaling pathway | 11 | 13.97604962 |
| GOTERM_CC_DIRECT | mmu04360:Axon guidance | 8 | 8.657491879 |
| GOTERM_MF_DIRECT | mmu04730:Long-term depression | 5 | 8.273286919 |
| GOTERM_MF_DIRECT | mmu04925:Aldosterone synthesis and secretion | 6 | 8.025647526 |
| GOTERM_MF_DIRECT | mmu04510:Focal adhesion | 8 | 7.819253967 |
| GOTERM_MF_DIRECT | mmu04070:Phosphatidylinositol signaling system | 5 | 5.905605906 |
| GOTERM_MF_DIRECT | m_plcdPathway:Phospholipase C d1 in phospholipid associated cell signaling | 2 | 4.333272899 |
| GOTERM_MF_DIRECT | GO:0030010 ~ establishment of cell polarity | 6 | 14.84265555 |
| GOTERM_MF_DIRECT | GO:0007420 ~ brain development | 10 | 9.291692541 |
| GOTERM_MF_DIRECT | GO:0030198 ~ extracellular matrix organization | 8 | 8.723977207 |
| GOTERM_MF_DIRECT | GO:0007399 ~ nervous system development | 12 | 7.879202652 |
| GOTERM_MF_DIRECT | GO:0007030 ~ Golgi organization | 6 | 7.848307704 |
| KEGG_PATHWAY | GO:0015031 ~ protein transport | 15 | 7.756581427 |
| KEGG_PATHWAY | GO:0016020 ~ membrane | 100 | 17.7794164 |
| KEGG_PATHWAY | GO:0005737 ~ cytoplasm | 105 | 16.41697626 |
| KEGG_PATHWAY | GO:0005794 ~ Golgi apparatus | 31 | 13.40458113 |
| KEGG_PATHWAY | GO:0030315 ~ T-tubule | 6 | 11.00613272 |
| KEGG_PATHWAY | GO:0043005 ~ neuron projection | 15 | 8.74749388 |
| KEGG_PATHWAY | GO:0005856 ~ cytoskeleton | 26 | 8.386444372 |
| KEGG_PATHWAY | GO:0000166 ~ nucleotide binding | 33 | 11.0905486 |
| KEGG_PATHWAY | GO:0035091 ~ phosphatidylinositol binding | 6 | 7.733881177 |
| KEGG_PATHWAY | GO:0005524 ~ ATP binding | 27 | 7.467695552 |
| BIOCARTA | GO:0005085 ~ guanyl-nucleotide exchange factor activity | 8 | 7.030604737 |