Table 1.
Homing receptors and ligands on vasculature
| Ligand on vasculature | Receptor on T cell | Effect of interaction |
| Naïve T cells | ||
| PNAd | CD62L | Rolling/Tethering |
| CCL19 | CCR7 | Integrin activation |
| CCL21 | CCR7 | Integrin activation |
| ICAM-1 | LFA1 | Firm adhesion/arrest |
| Effector T cells | ||
| PSGL-1 | P-selectin | Rolling/Tethering |
| ESL | E-selectin | Rolling/Tethering |
| HA | CD44 | Rolling/Tethering |
| CXCL9-11 | CXCR3 | Integrin activation |
| VCAM-1 | α4β1 | Firm adhesion/arrest |
| ICAM-1 | LFA1 | Firm adhesion/arrest |
| MAdCAM1 | α4β7 | Firm adhesion/arrest |
ESL, E-selectin ligand; HA, hyaluronic acid; ICAM-1, intracellular adhesion molecule 1; PNAd, peripheral node addressin; VCAM-1, vascular cell adhesion molecule 1.