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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Int J Biochem Cell Biol. 2023 Mar 16;158:106397. doi: 10.1016/j.biocel.2023.106397

Figure 1. Mitochondrial dynamics and stress response.

Figure 1.

Mitochondria dynamics is regulated by balanced fusion and fission. Fusion is regulated by Mfn1, Mfn2 and Opa1. Fission is regulated by Drp1, Fis1, and Mff. Imbalance in this homeostasis results in induction of mtUPR and mitophagy. Mfn1- Mitofusin-1; Mfn2- Mitofusin-2; Opa1- Optic atrophy type 1; Drp1- Dynamin-related Protein 1; Fis1-Fission-1; Mff-Mitochondrial Fission Factor; mtUPR- Mitochondrial Unfolded protein response