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. 2023 May;29(5):1015–1019. doi: 10.3201/eid2905.221617

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Genetic relationship of HuCV2 from 2 patients in China to other circoviruses. A, B) Pairwise identities of the rep (A) and cap (B) protein of HuCV2 isolate YN09/J030 to other circoviruses. C) Comparison of main residues in the conserved domains of rep protein (RCR and SF3 helicase motifs) between HuCV2 isolates YN09/J030 and YN09/347 and other circoviruses. Asterisks (*) indicate unique residues that are different from PCV3 or WoCV. BatCV, bat-associated circovirus; BearCV, bear-associated circovirus; Cap, capsid protein; HuCV, human-associated circovirus; PagumaCV, paguma circovirus; PCV, porcine circovirus; RCR, rolling circle replication; Rep, replication-associated protein; RoCV, rodent-associated circovirus; SF3, superfamily 3; WoCV, wolverine-associated circovirus.