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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Transplantation. 2022 Mar 23;106(9):1717–1719. doi: 10.1097/TP.0000000000004097

TABLE 1.

Known carbohydrate xenoantigens expressed on pig cells

Carbohydrate Responsible enzyme Gene-knockout
pig
Gal α-1,3-galactosyltransferase GTKO
Neu5Gc CMAH CMAHKO
Sda β-1,4 N-acetylgalactosaminyl transferase β 4GalNT2KO

CMAH, cytidine monophosphate N-acetylneuraminic acid hydroxylase; Gal, galactose-α1, 3-galactose; Neu5Gc, N-glycolylneuraminic acid.