Table 4.

Single factor analysis

Exposure	Statistics	STAGE continuous
MTF1	2.0 ± 0.4	– 0.0 (– 0.3, 0.2) 0.9016
MTF1 tertile
Low	116 (33.4%)	0
Middle	115 (33.1%)	0.2 (0.0, 0.5) 0.0315
High	116 (33.4%)	0.2 (– 0.0, 0.4) 0.0701
Gender
1	217 (62.5%)	0
2	130 (37.5%)	0.1 (– 0.1, 0.3) 0.3366
Age	65.7 ± 10.5	– 0.0 (– 0.0, 0.0) 0.0621
Age tertile
Low	116 (33.4%)	0
Middle	113 (32.6%)	– 0.0 (– 0.3, 0.2) 0.7437
High	118 (34.0%)	– 0.2 (– 0.5, – 0.0) 0.0432
Grade
1	7 (2.0%)	0
2	120 (34.6%)	0.1 (– 0.6, 0.7) 0.8488
3	220 (63.4%)	0.3 (– 0.4, 0.9) 0.3740
Group
1	318 (91.6%)	0
2	29 (8.4%)	– 0.2 (– 0.6, 0.1) 0.1562
T
1	19 (5.5%)	0
2	74 (21.3%)	0.7 (0.4, 1.0) < 0.0001
3	162 (46.7%)	1.6 (1.3, 1.9) < 0.0001
4	92 (26.5%)	2.1 (1.8, 2.4) < 0.0001
N
1	112 (32.3%)	0
2	94 (27.1%)	1.0 (0.8, 1.2) < 0.0001
3	75 (21.6%)	1.3 (1.1, 1.4) < 0.0001
4	66 (19.0%)	1.6 (1.4, 1.8) < 0.0001
M
1	323 (93.1%)	0
2	24 (6.9%)	1.6 (1.3, 1.9) < 0.0001

MTF1 metal regulatory transcription factor 1