Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 24;3:58. doi: 10.1038/s43856-023-00277-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a SARS-CoV-2 Spike-specific CD4 + T cells at 0, 21, and 90 stratified by age group (<65 years [light blue], 65–74 years [blue], ≥75 years [dark blue]). Group sizes are; at day 0 n = 142 (<65 years), n = 54 (65–74 years), n = 90 (≥75 years); at day 21 n = 234 (<65 years), n = 123 (65–74 years), n = 103 (≥75 years); at day 90 n = 214 (<65 years), n = 134 (65–74 years), n = 114 (≥75 years). b SARS-CoV-2 Spike-specific CD8 + T cells at 0, 21, and 90 stratified by age group (<65 years [light blue], 65–74 years [blue], ≥75 years [dark blue]). Group sizes are; at day 0 n = 139 (<65 years), n = 54 (65–74 years), n = 79 (≥75 years); at day 21 n = 233 (<65 years), n = 118 (65–74 years), n = 93 (≥75 years); at day 90 n = 213 (<65 years), n = 130 (65–74 years), n = 106 (≥75 years). c SARS-CoV-2 Spike-specific CD4 + T cells at day 90 in the three age groups stratified by Charlson Comorbidity Index (CCI) (CCI = 0 [light green], CCI = 1–2 [green], CCI > 2 [dark green]). Group sizes are; in age group <65 years n = 175 (CCI = 0), n = 30 (CCI = 1–2), n = 9 (CCI > 2); age group 65–74 years n = 88 (CCI = 0), n = 37 (CCI = 1–2), n = 5 (CCI > 2); age group ≥75 n = 79 (CCI = 0), n = 21 (CCI = 1–2), n = 6 (CCI > 2). d SARS-CoV-2 Spike-specific CD8 + T cells at day 90 in the three age groups stratified by CCI (CCI = 0 [light green], CCI = 1–2 [green], CCI > 2 [dark green]). Group sizes are; in age group <65 years n = 175 (CCI = 0), n = 29 (CCI = 1–2), n = 9 (CCI > 2); age group 65–74 years n = 88 (CCI = 0), n = 37 (CCI = 1–2), n = 5 (CCI > 2); age group ≥75 n = 79 (CCI = 0), n = 21 (CCI = 1–2), n = 6 (CCI > 2). Data was compared using unpaired, non-parametric Mann–Whitney U-test. Error bars show the distribution within 1.5 times IQR. p-value annotation legend: *1.00·10⁻⁰² < p ≤ 5.00·10⁻⁰², **1.00·10⁻⁰³ < p ≤ 1.00·10⁻⁰², ***1.00·10⁻⁰⁴ < p ≤ 1.00·10⁻⁰³, ****p ≤ 1.00·10⁻⁰⁴.