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. 2023 Apr 24;3:58. doi: 10.1038/s43856-023-00277-x

Fig. 3. SARS-CoV-2 Spike IgG by age and Charlson Comorbidities Index (CCI).

Fig. 3

a SARS-CoV-2 Spike IgG arbitrary units (AU)/ml at day 0, 21, and 90 stratified by age group (<65 years [light blue], 65–74 years [blue], ≥75 years [dark blue]). Group sizes are; at day 0 n = 352 (<65 years), n = 154 (65–74 years), n = 144 (≥75 years); at day 21 n = 304 (<65 years), n = 152 (65–74 years), n = 142 (≥75 years); at day 90 n = 238 (<65 years), n = 146 (65–74 years), n = 139 (≥75 years). b SARS-CoV-2 Spike IgG at day 90 in the three age groups stratified by Charlson Comorbidity Index (CCI) (CCI = 0 [light green], CCI = 1–2 [green], CCI > 2 [dark green]). Group sizes are; in age group <65 years n = 195 (CCI = 0), n = 33 (CCI = 1–2), n = 10 (CCI > 2); age group 65–74 years n = 92 (CCI = 0), n = 46 (CCI = 1–2), n = 8 (CCI > 2); age group ≥ 75 n = 97 (CCI = 0), n = 32 (CCI = 1–2), n = 10 (CCI > 2). Data was compared using unpaired, non-parametric Mann–Whitney U-test. Error bars show the distribution within 1.5 times IQR. p-value annotation legend: *1.00·10−02 < p ≤ 5.00·10−02, **1.00·10−03 < p ≤ 1.00·10−02, ***1.00·10−04 < p ≤ 1.00·10−03, ****p ≤ 1.00·10−04.