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. 2023 Apr 24;3:58. doi: 10.1038/s43856-023-00277-x

Fig. 4. SARS-CoV-2 Spike-specific T cells at day 90 by serological vaccine responder group.

Fig. 4

Day 90 SARS-CoV-2 Spike-specific T cells stratified by serological vaccine responder group (Hypo [light blue], Moderate [blue], High [dark blue]). Serological vaccine responder group was defined based on the change in Spike IgG at day 90 relative to their pre-vaccine (baseline) levels: vaccine hypo-, moderate- and high responders were individuals with a log10 fold change of <2, 2-3, or >3 in Spike IgG, respectively. a SARS-CoV-2 Spike-specific CD4 + T cells; n = 46 (Hypo), n = 105 (Moderate), n = 318 (High). b SARS-CoV-2 Spike-specific CD8 + T cells; n = 36 (Hypo), n = 101 (Moderate), n = 309 (High). Data was compared using unpaired, non-parametric Mann–Whitney U-test. Error bars show the distribution within 1.5 times IQR. p-value annotation legend: *1.00·10−02 < p ≤ 5.00·10−02, **: 1.00·10−03 < p ≤ 1.00·10−02, ***1.00·10−04 < p ≤ 1.00·10−03, ****p ≤ 1.00·10−04.