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. 2023 Apr 24;3:58. doi: 10.1038/s43856-023-00277-x

Fig. 5. Risk factors for cellular COVID-19 vaccine hypo-responsiveness.

Fig. 5

a Forest plot of adjusted odds ratios (aOR) for cellular CD4 + hypo-responsiveness with 95% confidence intervals (CI). Number of hypo-responders and responders, respectively, for each variable from top to bottom is; n = 25 and n = 206 (Female), n = 36 and n = 186 (Male), n = 20 and n = 185 (<65 years), n = 11 and n = 123 (65–74 years), n = 30 and n = 84 (≥75 years), n = 36 and n = 306 (CCI = 0), n = 19 and n = 72 (CCI = 1–2), n = 6 and n = 14 (CCI > 2), n = 56 and n = 184 (BNT162b2), n = 5 and n = 208 (mRNA-1273). b Forest plot of adjusted odds ratios (aOR) for cellular CD8 + hypo-responsiveness with 95% confidence intervals. Number of hypo-responders and responders, respectively, for each variable from top to bottom is; n = 55 and n = 172 (Female), n = 61 and n = 152 (Male), n = 44 and n = 160 (<65 years), n = 29 and n = 101 (65–74 years), n = 43 and n = 63 (≥75 years), n = 75 and n = 258 (CCI = 0), n = 32 and n = 55 (CCI = 1–2), n = 9 and n = 11 (CCI > 2), n = 98 and n = 130 (BNT162b2), n = 18 and n = 194 (mRNA-1273). Data was assessed in a multivariable logistical regression including sex, age group, Charlson Comorbidity Index (CCI) score, and vaccine type as predictors. Participants receiving ChAdOx1 as their first dose were excluded from the model given the small sample size (n = 9).