Table 1.
Baseline demographic characteristics of male aged
| Rat ID | Weight, g | Fat, g | Lean, g | Microbiome | Metabolomics | Transcriptomic |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| PFC | Hippocampus | Colon | Liver | Muscle | ||||||
| ConSed3 | 573.00 | 153.07 | 377.83 | X | X | X | X | X | X | X |
| ConSed4 | 568.00 | 116.82 | 408.34 | X | X | X | X | X | X | X |
| ConSed6 | 572.00 | 114.14 | 412.19 | X | X | X | X | X | X | X |
| ConSed7 | 583.00 | 140.07 | 401.44 | x | X | X | X | X | X | X |
| ConSed8 | 585.00 | 126.52 | 416.90 | X | X | X | X | X | X | X |
| ConSed9 | 573.00 | 130.35 | 400.31 | X | X | |||||
| ConSed10 | 583.00 | 140.07 | 401.44 | X | X | X | X | X | X | X |
| ConSed11 | 585.00 | 126.52 | 416.90 | X | X | |||||
| ConSed12 | 573.00 | 130.35 | 400.31 | X | X | |||||
| ConSed13 | 555.00 | 110.56 | 405.16 | X | X | |||||
| ConSed14 | 528.00 | 98.80 | 390.03 | X | X | |||||
| ConSed15 | 557.00 | 112.86 | 401.51 | X | X | |||||
| ConEx5 | 564.00 | 132.17 | 389.73 | X | X | X | X | X | X | X |
| ConEx7 | 547.00 | 97.35 | 405.86 | X | X | X | X | X | X | X |
| ConEx9 | 540.00 | 103.60 | 395.66 | X | X | X | X | X | X | X |
| ConEx10 | 553.00 | 131.46 | 379.43 | X | X | X | X | X | X | X |
| ConEx11 | 508.00 | 99.40 | 367.30 | X | X | X | X | X | X | X |
| ConEx12 | 558.00 | 120.33 | 392.73 | X | X | X | X | X | X | X |
| ConEx13 | 613.00 | 138.72 | 419.57 | X | X | |||||
| ConEx14 | 528.00 | 102.22 | 387.59 | X | X | |||||
| ConEx15 | 541.00 | 93.82 | 408.08 | X | X | |||||
| ConEx16 | 575.00 | 137.31 | 395.14 | X | X | |||||
| ConEx17 | 592.00 | 134.26 | 413.79 | X | X | |||||
| ConEx18 | 645.00 | 181.08 | 415.11 | X | X | |||||
| ConEx19 | 531.00 | 84.81 | 410.03 | X | X | |||||
| LPSed4 | 555.00 | 111.90 | 403.35 | X | X | X | X | X | X | X |
| LPSed5 | 548.00 | 103.60 | 399.50 | X | X | X | X | X | X | X |
| LPSed7 | 514.00 | 94.40 | 379.70 | X | X | X | X | X | X | X |
| LPSed8 | 516.00 | 93.33 | 384.77 | X | X | X | X | X | X | X |
| LPSed9 | 556.00 | 99.21 | 411.05 | X | X | |||||
| LPSed10 | 556.00 | 99.21 | 411.05 | X | X | X | X | X | X | X |
| LPSed13 | 582.00 | 132.53 | 399.78 | X | X | X | X | X | X | X |
| LPSed14 | 538.00 | 110.52 | 390.53 | X | X | |||||
| LPSed16 | 542.00 | 119.67 | 383.99 | X | X | |||||
| LPSed17 | 548.00 | 94.96 | 414.44 | X | X | |||||
| LPSed18 | 588.00 | 129.19 | 416.38 | X | X | |||||
| LPEx3 | 530.00 | 101.52 | 389.10 | X | X | X | X | X | X | |
| LPEx4 | 521.00 | 105.37 | 382.18 | X | X | X | X | X | X | X |
| LPEx5 | 557.00 | 114.24 | 403.53 | X | X | |||||
| LPEx6 | 498.00 | 82.35 | 378.05 | X | X | X | X | X | X | X |
| LPEx7 | 538.00 | 106.13 | 394.34 | X | X | |||||
| LPEx8 | 504.00 | 91.95 | 378.75 | X | X | X | X | X | X | X |
| LPEx9 | 534.00 | 109.67 | 382.51 | X | X | |||||
| LPEx10 | 569.00 | 115.62 | 408.32 | X | X | X | X | X | X | X |
| LPEx11 | 536.00 | 123.91 | 372.75 | X | X | X | X | X | X | X |
| LPEx12 | 564.00 | 125.16 | 393.83 | X | X | |||||
| LPEx13 | 539.00 | 98.03 | 399.94 | X | X | |||||
| LPASed4 | 555.00 | 86.81 | 392.66 | X | X | X | X | X | X | X |
| LPASed5 | 532.00 | 99.89 | 395.56 | X | X | X | X | X | X | X |
| LPASed6 | 481.00 | 82.74 | 366.14 | X | X | X | X | X | X | X |
| LPASed7 | 522.00 | 98.66 | 386.20 | X | X | X | X | X | X | X |
| LPASed8 | 565.00 | 101.93 | 419.22 | X | X | |||||
| LPASed9 | 515.00 | 96.34 | 377.39 | X | X | X | X | X | X | X |
| LPASed11 | 536.00 | 115.5 | 376.15 | X | X | X | X | X | X | X |
| LPASed12 | 552.00 | 114.91 | 392.39 | X | X | |||||
| LPASed13 | 537.00 | 101.76 | 395.24 | X | X | |||||
| LPAEx4 | 562.00 | 105.21 | 415.97 | X | X | X | X | X | X | X |
| LPAEx6 | 505.00 | 69.33 | 399.57 | X | X | X | X | X | X | X |
| LPAEx7 | 522.00 | 105.63 | 380.77 | X | X | X | X | X | X | X |
| LPAEx8 | 537.00 | 99.59 | 400.37 | X | X | |||||
| LPAEx9 | 531.00 | 102.59 | 386.59 | X | X | X | X | X | X | X |
| LPAEx11 | 483.00 | 96.10 | 348.57 | X | X | X | X | X | X | X |
| LPAEx12 | 545.00 | 113.11 | 387.36 | X | X | X | X | X | X | X |
| LPAEx13 | 609.00 | 136.52 | 423.53 | X | X | |||||
CONEx, control + exercise group; CONSed, control + sedentary group; DEG, differential expressed genes; FDR, false discovery rate; LPEx, Lactobacillus paracasei + exercise group; LPSed, Lactobacillus paracasei + sedentary group; LPAEx, Lactobacillus paracasei expressing angiotensin (1–7) + exercise group; LPASed, Lactobacillus paracasei + sedentary group.