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. Author manuscript; available in PMC: 2023 Apr 24.
Published in final edited form as: Nat Chem Biol. 2022 Feb 24;18(4):412–421. doi: 10.1038/s41589-022-00971-2

Extended Data Figure 11. Effect of bortezomib and lumacaftor on mutant CFTR levels.

Extended Data Figure 11.

CFBE41o-4.7 cells expressing ΔF508-CFTR were treated with vehicle DMSO, bortezomib (1 μM), or lumacaftor (1 μM) for 24 h and CFTR and loading control GAPDH levels were assessed by Western blotting. The gel shown is representative of n=3 biologically independent samples/group.