TABLE 1.
Clinical characteristics of patients with SSN growth and SSN stable under long‐term follow‐up
| Characteristic | Total patients (n = 306) | Patients with SSN growth (n = 163) | Patients with SSN stable (n = 143) | p value |
|---|---|---|---|---|
| Age | 67.0 (59.0–77.0) | 71.0 (63.0–80.0) | 64.0 (56.0–71.0) | <0.001 |
| Sex | 0.059 | |||
| Female | 215 (70.3%) | 107 (65.6%) | 108 (75.5%) | |
| Male | 91 (29.7%) | 56 (34.4%) | 35 (24.5%) | |
| Smoking history | 0.289 | |||
| Current smoker | 19 (6.2%) | 13 (8.0%) | 6 (4.2%) | |
| Ex‐smoker | 28 (9.2%) | 15 (9.2%) | 13 (9.1%) | |
| Nonsmoker | 259 (84.6%) | 135 (82.8%) | 124 (86.7%) | |
| Pack‐years | 20.0 (10.3–30.0) | 20.0 (12.5–30.0) | 15.0 (5.0–30.0) | 0.073 |
| Previous history of lung disease | 0.208 | |||
| Emphysema | 3 (1.0%) | 2 (1.2%) | 1 (0.7%) | |
| Bronchiectasis | 5 (1.6%) | 5 (3.1%) | 0 (0.0%) | |
| Chronic bronchitis | 8 (2.6%) | 5 (3.1%) | 3 (2.1%) | |
| Tuberculosis | 12 (3.9%) | 6 (3.7%) | 6 (4.2%) | |
| Previous history of cancer | ||||
| Lung cancer | 69 (22.5%) | 36 (22.1%) | 33 (23.1%) | 0.836 |
| Other cancer | 81 (26.5%) | 38 (23.3%) | 43 (30.1%) | 0.181 |
| Family history of cancer | 33 (10.8%) | 17 (10.4%) | 16 (11.2%) | 0.977 |
| Number of concurrent SSNs per patient | 0.562 | |||
| 1 | 261(85.3%) | 142 (87.1%) | 119 (83.2%) | |
| 2 | 35 (11.4%) | 17 (10.4%) | 18 (12.6%) | |
| 3 | 10 (3.3%) | 4 (2.5%) | 6 (4.2%) | |
Note: Values are expressed as a number (%) or the median (interquartile range).
Abbreviation: SSN, subsolid nodule.