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. 2023 Apr 24;13:6622. doi: 10.1038/s41598-023-33213-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Exploring key module eigengenes associated with the NMlow/TMEhigh and NMlow/TMElow groups using weighted gene co-expression network analysis. (A) Evaluation of the scale-free fit index for differing soft-thresholding powers (β) and examination of the connectivity of various soft-thresholding powers. (B) A heatmap depicts the association between module eigengenes and various subgroups. (C) Functional enrichment analysis of key module eigengenes. NM nucleotide metabolism, TME tumour microenvironment.