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Representative samples stained with CD63 (red) and EGFR (green). CD63 colocalizes with EGFR in intracellular and extracellular vesicles in PTC (Colocalization coefficient >0.7) (A, B). (C) In NIFTP CD63 positive vesicles appear mainly in the cytoplasm of tumor cells along with EGFR that shows enrichment at the plasma membrane.
