Table 2.
EGFR expression in relation to pathological characteristics in PTC samples.
| Pathological characteristic | |||||||
|---|---|---|---|---|---|---|---|
| Invasion | Lymph node metastasis | BRAF mutation status | |||||
| Groups | pos (n=26) | neg (n=14) | pos (n=14) | neg (n=26) | pos (n=16) | neg (n=25) | |
| EGFR | Average ΔCt | 2.81 | 3.17 | 2.56 | 3.20 | 1.86 | 3.80 |
| Fold change (pos/neg) | 1.29 | 1.55 | -3.84 | ||||
| p-value* | 0.379 | 0.286 | 0.077 | ||||
Expression is calculated using the relative quantification method (ΔCt = CT of target normalized to CT of housekeeping gene). Fold change is calculated using (2–ΔΔCT) formula. *Statistical analysis is done using student t-test.