Table 3.
Comparison of symptom prevalence at baseline and week 4 between the groups.
| Symptom | Total prevalence | TOLF-HF group (n = 29), n (%) | Control group (n = 31), n (%) | χ 2 | P value* |
|---|---|---|---|---|---|
| Shortness of breath | |||||
| Baseline | 45 (75.0) | 20 (69.0) | 25 (80.6) | 0.556 | 0.456 |
| Week 4 | 28 (46.7) | 9 (31.0) | 19 (61.3) | 4.362 | 0.037 |
| Difficulty breathing when lying flat | |||||
| Baseline | 44 (73.3) | 20 (69.0) | 24 (77.4) | 0.201 | 0.654 |
| Week 4 | 11 (18.3) | 4 (13.8) | 7 (22.6) | 0.297 | 0.586 |
| Cough | |||||
| Baseline | 37 (61.7) | 17 (58.6) | 20 (64.5) | 0.041 | 0.839 |
| Week 4 | 22 (36.7) | 7 (24.1) | 15 (48.4) | 2.822 | 0.093 |
| Lack of energy | |||||
| Baseline | 31 (51.7) | 15 (51.7) | 16 (51.6) | 0.000 | 1.000 |
| Week 4 | 19 (31.7) | 6 (20.7) | 13 (41.9) | 2.221 | 0.136 |
| Swelling of arms or legs | |||||
| Baseline | 30 (50.0) | 11 (37.9) | 19 (61.3) | 2.403 | 0.121 |
| Week 4 | 17 (28.3) | 4 (13.8) | 13 (41.9) | 4.540 | 0.033 |
| Waking up breathless at night | |||||
| Baseline | 26 (43.3) | 11 (37.9) | 15 (48.4) | 0.309 | 0.578 |
| Week 4 | 18 (30.0) | 6 (20.7) | 12 (38.7) | 1.538 | 0.215 |
*
P values were derived from the Pearson's χ2 test with continuity correction.