Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 11;11:1143852. doi: 10.3389/fcell.2023.1143852

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Vedder, Reinberger, Haider, Eichelmann, Odenthal, Abdelilah-Seyfried, Aherrahrou, Breuer and Erdmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Quantitative data analysis with pyHeart4Fish. Analysis of treated fish with pyHeart4Fish revealed multiple functional heart phenotypes. (A) The left graph presents the detected heart rate derived from the fast fourier transformation (FFT). The right graph displays the approximate heart size in µm². (B) Percentual data on the severity of manually assessed pericardial edema in treated Tg(myl7:eGPF)^twu34/+ zebrafish. (C) The relative contractility derived from percentual size changes of each heart chamber (left graph). Approximate ejection fraction determined by chamber volume changes (right graph). (D) Mean max. heart chamber size (dilation) is presented on the left, while the mean min. heart chamber size (max. contraction) is displayed on the right. The number of fish analyzed is shown in brackets after the treatment condition. Dotted gray lines indicate z-scores of ±1.96 and statistical significance with an alpha error of 5%.