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. 2023 Apr 11;14:1126119. doi: 10.3389/fphar.2023.1126119

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Copyright © 2023 Otkur, Liu, Chen, Li, Ling, Lin, Yang, Xia, Qi and Piao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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YAP/TAZ activity was required for anchorage-independent growth of CRC cells. (A,B) Representative microscopic images and quantification analysis of colony formation assay (n = 3) of HCT116 cell lines in soft agar assay. Scale bars: 0.5 cm. (C,D) Representative microscopic images and quantification analysis of colony formation assay (n = 3) of DLD1 cell lines in soft agar assay. Scale bars: 0.5 cm. Verteporfin 5 μM was used, and the culture medium was replaced every 3 days.