TABLE 5.
Univariable and multivariable linear regression models in AD dementia
| Informal care hours per day | NPI‐Q caregiver distress | GDS | EQ‐5D | VAS | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Univariable | Multivariable | Univariable | Multivariable | Univariable | Multivariable | Univariable | Multivariable | Univariable | Multivariable | |
| Β (SE) | Β (SE) | Β (SE) | Β (SE) | Β (SE) | Β (SE) | Β (SE) | Β (SE) | Β (SE) | Β (SE) | |
| Patient determinants | ||||||||||
| Age | −0.0001 (0.01) | −0.01 (0.02) | 0.01 (0.01) | 0.0002 (0.01) | −0.002 (0.01) | 0.005 (0.01) | −0.001 (0.001) | −0.003 (0.001) | −0.01 (0.003)* | −0.01 (0.01) |
| MMSE | −0.02 (0.02) | 0.01 (0.02) | −0.03 (0.02)* | 0.01 (0.01) | −0.01 (0.01) | 0.01 (0.01) | −0.001 (0.001) | −0.001 (0.001) | −0.003 (0.005) | −0.003 (0.05) |
| CCI | −0.10 (0.07) | −0.04 (0.09) | −0.02 (0.06) | 0.03 (0.05) | −0.07 (0.04) | −0.04 (0.06) | −0.0004 (0.005) | 0.01 (0.01) | −0.02 (0.02) | 0.01 (0.03) |
| NPI‐Q severity | 0.04 (0.01) a | 0.03 (0.01)* | 0.13 (0.01) a | 0.012 (0.01) a | 0.04 (0.01) a | 0.03 (0.01) a | −0.001 (0.001) | −0.001 (0.001) | −0.004 (0.003) | −0.003 (0.004) |
| Amsterdam IADL | −0.03 (0.01) a | −0.02 (0.01) a | −0.04 (0.01) a | −0.01 (0.004) a | −0.02 (0.004) a | −0.03 (0.005)* | 0.0003 (0.0005) | −0.0001 (0.001) | 0.002 (0.002) | 0.002 (0.002) |
| Care partner determinants | ||||||||||
| Age | 0.02 (0.01)* | 0.01 (0.01) | −0.004 (0.01) | −0.001 (0.01) | −0.003 (0.01) | −0.004 (0.01) | 0.0001 (0.001) | 0.0002 (0.001) | −0.001 (0.002) | 0.0003 (0.004) |
| Sex, female | 0.02 (0.15) | 0.08 (0.16) | 0.11 (0.15) | −0.004 (0.10) | 0.27 (0.11)* | 0.26 (0.11)* | −0.03 (0.01)* | −0.002 (0.01) | −0.07 (0.04) | −0.05 (0.05) |
| Relation to patient, spouse | 0.84 (0.24) a | 0.84 (0.29) a | −0.16 (0.23) | 0.09 (0.17) | 0.18 (0.17) | 0.31 (0.21) | 0.01 (0.02) | 0.01 (0.02) | 0.04 (0.06) | 0.04 (0.09) |
*
Significant based on P < 0.05.
a
Significant based on P < 0.01.
Notes: Data are represented as beta coefficients (SE) and odds ratio (95% CI). Analyses were not corrected for multiple testing.
Abbreviations: CCI, Charlson Comorbidity Index; CI, confidence interval; EQ‐5D, the European Quality of Life‐5 Dimensions; GDS, Geriatric Depression Scale; IADL, Instrumental Activities of Daily Living; MCI, mild cognitive impairment; MMSE, Mini‐Mental State Examination; NPI‐Q, Neuropsychiatric Inventory Questionnaire; RUD, Resource Utilization in Dementia; SCD, subjective cognitive decline; SE, standard error; VAS, Visual Analogue Scale.