Table 2.
Baseline characteristics for diabetic or non-diabetic patients with different ANC levels.
| Variables | ANC-L/Non-T2D (n = 2,260) |
ANC-H/Non-T2D (n = 1,940) |
ANC-L/T2D (n = 1,642) |
ANC-H/T2D (n = 1,984) |
P-value |
|---|---|---|---|---|---|
| Baseline characteristics | |||||
| Age, years | 58.30 ± 10.08 | 56.83 ± 10.40 | 59.94 ± 9.37 | 59.12 ± 10.36 | <0.001 |
| Male | 1,664 (73.6) | 1,601 (82.5) | 1,137 (69.2) | 1,502 (75.7) | <0.001 |
| BMI, kg/m2 | 25.41 ± 3.13 | 25.88 ± 3.26 | 26.04 ± 3.04 | 26.46 ± 3.25 | <0.001 |
| DM (%) | 0 (0.0) | 0 (0.0) | 1,642 (100.0) | 1,984 (100.0) | <0.001 |
| Hypertension | 1,339 (59.2) | 1,247 (64.3) | 1,113 (67.8) | 1,401 (70.6) | <0.001 |
| Dyslipidemia | 1,402 (62.0) | 1,251 (64.5) | 1,176 (71.6) | 1,387 (69.9) | <0.001 |
| Smoking history | 1,151 (50.9) | 1,236 (63.7) | 812 (49.5) | 1,179 (59.4) | <0.001 |
| Previous MI | 128 (5.7) | 86 (4.4) | 110 (6.7) | 136 (6.9) | 0.005 |
| Previous PCI/CABG | 421 (18.6) | 317 (16.3) | 395 (24.1) | 519 (26.2) | <0.001 |
| Previous stroke | 178 (7.9) | 176 (9.1) | 213 (13.0) | 252 (12.7) | <0.001 |
| Previous PAD | 146 (6.5) | 123 (6.3) | 158 (9.6) | 158 (8.0) | <0.001 |
| Clinical presentation | <0.001 | ||||
| SAP | 890 (39.4) | 603 (31.1) | 704 (42.9) | 674 (34.0) | |
| NSTE-ACS | 1,370 (60.6) | 1,337 (68.9) | 938 (57.1) | 1,310 (66.0) | |
| Laboratory tests | |||||
| Neutrophils, ∗109/L | 3.13 ± 0.60 | 5.40 ± 1.43 | 3.20 ± 0.57 | 5.77 ± 1.92 | <0.001 |
| Lymphocytes, ∗109/L | 1.82 ± 0.55 | 2.00 ± 0.66 | 1.91 ± 0.61 | 2.07 ± 0.73 | <0.001 |
| Platelet, ∗109/L | 164.73 ± 79.76 | 185.45 ± 91.30 | 161.19 ± 81.02 | 185.83 ± 91.57 | <0.001 |
| FBG, mmol/L | 5.12 ± 0.55 | 5.23 ± 0.61 | 7.24 ± 2.36 | 8.00 ± 2.89 | <0.001 |
| HbA1c, % | 5.86 ± 0.34 | 5.88 ± 0.33 | 7.41 ± 1.32 | 7.47 ± 1.37 | <0.001 |
| TG, mmol/L | 1.59 ± 0.87 | 1.81 ± 1.00 | 1.85 ± 1.31 | 1.93 ± 1.17 | <0.001 |
| TC, mmol/L | 4.19 ± 1.03 | 4.26 ± 1.05 | 4.21 ± 1.13 | 4.30 ± 1.10 | 0.003 |
| HDL-C, mmol/L | 1.09 ± 0.29 | 1.03 ± 0.28 | 1.04 ± 0.29 | 1.00 ± 0.25 | <0.001 |
| LDL-C, mmol/L | 2.50 ± 0.88 | 2.55 ± 0.90 | 2.49 ± 0.93 | 2.59 ± 0.92 | 0.002 |
| hsCRP, mg/L | 2.08 ± 2.66 | 3.83 ± 4.11 | 2.42 ± 2.95 | 4.34 ± 4.33 | <0.001 |
| Creatinine, μmol/L | 73.21 ± 13.64 | 76.35 ± 14.85 | 72.75 ± 15.15 | 77.00 ± 17.16 | <0.001 |
| eGFR, mL/min/1.73 m2 | 104.70 ± 20.57 | 102.42 ± 21.09 | 104.88 ± 23.23 | 100.33 ± 23.62 | <0.001 |
| LVEF, % | 64.56 ± 5.91 | 63.75 ± 6.54 | 64.17 ± 6.35 | 62.50 ± 6.99 | <0.001 |
| Medications | |||||
| Aspirin | 2,232 (98.8) | 1,912 (98.6) | 1,628 (99.1) | 1,958 (98.7) | 0.429 |
| Clopidogrel | 2,225 (98.5) | 1,915 (98.7) | 1,624 (98.9) | 1,963 (98.9) | 0.472 |
| β-blocker | 1,983 (87.7) | 1,719 (88.6) | 1,492 (90.9) | 1,826 (92.0) | <0.001 |
| CCB | 1,126 (49.8) | 970 (50.0) | 861 (52.4) | 1,053 (53.1) | 0.085 |
| Statins | 2,191 (96.9) | 1,864 (96.1) | 1,556 (94.8) | 1,894 (95.5) | 0.005 |
| Nitrate | 2,209 (97.7) | 1,917 (98.8) | 1,604 (97.7) | 1,932 (97.4) | 0.011 |
| Procedural data | |||||
| LM/three-vessel disease | 858 (38.0) | 755 (38.9) | 771 (47.0) | 979 (49.3) | <0.001 |
| CTO lesions | 163 (7.2) | 129 (6.6) | 114 (6.9) | 137 (6.9) | 0.915 |
| Bifurcation lesions | 457 (20.2) | 397 (20.5) | 312 (19.0) | 400 (20.2) | 0.709 |
| Number of treated vessels | 1.37 ± 0.62 | 1.40 ± 0.65 | 1.41 ± 0.65 | 1.47 ± 0.72 | <0.001 |
| Number of stents | 1.83 ± 1.01 | 1.88 ± 1.01 | 1.92 ± 1.07 | 1.97 ± 1.08 | <0.001 |
| SYNTAX score | 10.89 ± 7.20 | 11.72 ± 7.59 | 11.93 ± 7.61 | 12.73 ± 8.03 | <0.001 |
Values are mean ± standard deviation or n (%).
Abbreviations as in Table 1 .