Table 1.
Demographic and clinic-pathological characteristics of the study population
| Ctrl (n = 16) |
Exp (n = 33) |
MPM (n = 32) |
Pre-diagnostic samples (n = 7) | Total (n = 88) |
p-Value | |
|---|---|---|---|---|---|---|
| Age (years) | 60.8 ± 17.8 | 70.2 ± 7.7 | 70.7 ± 6.7 | 75.9 ± 4.7 | 69.1 ± 10.6 | p = 0.002 |
| Gender (M/F) | 13/3 | 32/1 | 29/3 | 7/0 | 81/7 | p = 0.228 |
|
Smoking (n/%) Yes No Former |
6 (38) 5 (31) 5 (31) |
1 (4) 16 (48) 16 (48) |
5 (16) 11 (34) 16 (50) |
0 (0) 5 (71) 2 (29) |
12 (14) 37 (42) 39 (44) |
p = 0.025 |
|
Asbestos exposure Duration work (years) Cf (ff/l) × years ARD (Yes/No/ND) PD (Yes/No/ND) |
- - - - |
25.9 ± 10.3 3.5 ± 5.8 22/11/0 17/16/0 |
24.0 ± 12.5 5.8 ± 7.6 11/2/19 1/11/20 |
19.0 ± 1.79.3 ± 8.4 7/0/0 1/6/0 |
25.0 ± 11.4 4.5 ± 6.7 40/13/19 19/33/20 |
p = 0.215 p = 0.057 p = 0.001 p = 0.0005 |
|
Histotypes (n/%) Epithelial Biphasic Sarcomatoid |
19 (62) 6 (19) 6 (19) |
4 (57) 0 (0) 3 (43) |
23 (60) 6 (16) 9 (24) |
|||
| Overall survival (months) | - | - | 14.6 ± 9.8 |
Cf, Cumulative fibers; ARDs, asbestos-related diseases; PDs, pulmonary diseases