表 5.
匹配后两组IL-6、IL-8及TNF-α基因各位点情况比较
位点 | 研究组 (n=67) |
对照组 (n=67) |
统计值 | P值 |
IL-6(rs1800795) | ||||
CC | 19 | 11 | 6.064 | 0.014 |
CG | 39 | 36 | ||
GG | 9 | 20 | ||
C | 77 | 58 | 5.328 | 0.020 |
G | 57 | 76 | ||
IL-8(rs4073) | ||||
AA | 17 | 19 | 0.013 | 0.909 |
AT | 32 | 29 | ||
TT | 18 | 19 | ||
A | 66 | 67 | 0.015 | 0.903 |
T | 68 | 67 | ||
IL-8(rs2227306) | ||||
CC | 20 | 24 | 0.986 | 0.321 |
CT | 26 | 27 | ||
TT | 21 | 16 | ||
C | 66 | 75 | 1.212 | 0.271 |
T | 68 | 59 | ||
TNF-α(rs1800629) | ||||
GG | 42 | 60 | 13.271 | < 0.001 |
GA | 20 | 6 | ||
AA | 5 | 1 | ||
G | 104 | 128 | 18.483 | < 0.001 |
A | 30 | 6 | ||
TNF-α(rs1799724) | ||||
CC | 54 | 59 | 1.421 | 0.233 |
CT | 11 | 7 | ||
TT | 2 | 1 | ||
C | 119 | 125 | 1.648 | 0.199 |
T | 15 | 9 |