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. 2023 Apr 21;6(5):e202201703. doi: 10.26508/lsa.202201703

Figure 4. Inhibition of SOCS2 restored the effect of DNMT3A knockdown in pancreatic cells.

Figure 4.

Plasmid sh-SOCS2 was transfected into PANC-1 and Capan-1 cells, and cells were divided into four groups: sh-NC, sh-DNMT3A, sh-SOCS2, and sh-DNMT3A + sh-SOCS2. (A, B) SOCS2 expression in different groups. (C) EdU assay suggested the proliferation of treated cells. (D, E) The migration and invasion capacities of PC cells were analyzed by wound healing and transwell assays. *P < 0.05, **P < 0.01, and ***P < 0.001.