Skip to main content
. 2023 Apr 25;13(19):12889–12905. doi: 10.1039/d3ra01931d

Inhibitory assessment of the screened compounds 5a and 5b in comparison with cabozantinib against c-Meta.

Compound no. c-Met
IC50 (mean ± SEM) (nM)
5a 4.27 ± 0.31
5b 7.95 ± 0.17
Cabozantinib 5.38 ± 0.52
a

IC50: compound concentration required to inhibit the enzyme activity by 50%, SEM: standard error mean; each value is the mean of three values.