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STAT1 phosphorylation and Th17 cells. Levels of expression of pSTAT1 (a–d) or total STAT1 (e) on gated CD3+ T cells after stimulation with IFN-α. (f) Frequency of IL-17+ cells within CD4+ lymphocytes. Fold change was calculated as the MFI ratio between IFN-α-stimulated and non-stimulated cells. Each dot or number represents one individual. For (b and c), the mean of the HC group is shown as a dotted line and the standard deviation of the HC group as grey shading.
