Table 2.
Ordered logistic regression for arteriolosclerosis score in relation to DBP by dementia subtype
| Variables | Unadjusted analysis | Adjusted analysis | |||||
|---|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | P-value | Odds ratio | 95% CI | P-value | ||
| Frontal arteriolosclerosis score | |||||||
| Cohort | Alzheimer’s disease | 1.38 | 0.78–2.44 | 0.275 | 1.31 | 0.71–2.40 | 0.382 |
| Mixed | 5.69 | 2.62–12.4 | <0.001 | 5.41 | 2.52–11.6 | <0.001 | |
| Vascular dementia | 19.1 | 7.53–48.2 | <0.001 | 17.0 | 6.39–45.5 | <0.001 | |
| Age (y) | 1.03 | 1.00–1.06 | 0.074 | 1.04 | 1.00–1.07 | 0.030 | |
| DBP (after 65 years) | 1.07 | 1.04–1.10 | <0.001 | 1.07 | 1.03–1.11 | 0.001 | |
| Parietal arteriolosclerosis score | |||||||
| Cohort | Alzheimer’s disease | 2.09 | 1.11–3.94 | 0.022 | 2.28 | 1.18–4.40 | 0.014 |
| Mixed | 8.79 | 4.19–18.4 | <0.001 | 8.19 | 3.91–17.2 | <0.001 | |
| Vascular dementia | 18.1 | 5.74–57.3 | <0.001 | 17.0 | 4.63–62.3 | <0.001 | |
| Age (y) | 1.04 | 1.01–1.07 | 0.022 | 1.05 | 1.01–1.08 | 0.005 | |
| DBP (after 65 years) | 1.06 | 1.03–1.09 | <0.001 | 1.05 | 1.01–1.09 | 0.007 | |
Frontal n = 219, parietal n = 200.
Abbreviations: CI = confidence interval; DBP = diastolic blood pressure; y = years.
The unadjusted ordered logistic regression analysis shows the effects of each of the separate variables (DBP, disease subtype, age) on frontal arteriolosclerosis score. The adjusted analysis is the same regression of DBP on frontal arteriolosclerosis score in the presence of the covariates, age and disease subtype. Significant P-values are denoted in bold.