Table 1.
Baseline clinical features of patients with available follow-up angiography suitable for Murray law-based quantitative flow ratio (μQFR) analysis after drug-coated balloon (DCB) treatment of in-stent restenosis (ISR).
| Variables | VOCE (n = 20) | Non-VOCE (n = 149) | P |
|---|---|---|---|
| Age [years] | 59.90 ± 11.57 | 62.88 ± 9.58 | 0.20 |
| Female gender | 6 (30.00%) | 35 (23.49%) | 0.58 |
| BMI [kg/m2] | 25.12 ± 3.15 | 25.60 ± 3.31 | 0.54 |
| CAD risk factors: | |||
| Diabetes mellitus | 13 (65.00%) | 56 (37.58%) | 0.03 |
| Hypertension | 15 (75.00%) | 109 (73.15%) | 0.86 |
| Hyperlipidemia | 9 (45.00%) | 49 (32.88%) | 0.28 |
| Current smoker | 6 (30.00%) | 33 (22.15%) | 0.59 |
| Medical history: | |||
| Previous MI | 9 (45.00%) | 64 (42.95%) | 0.86 |
| Previous PCI | 20 (100.00%) | 149 (100.00%) | > 0.999 |
| Family history | 6 (30.00%) | 14 (9.39%) | 0.03 |
| Clinical presentation: | 0.25 | ||
| Silent ischemia | 0 (0.00%) | 15 (10.07%) | |
| Stable angina | 1 (5.00%) | 20 (13.42%) | |
| Unstable angina | 19 (95.00%) | 114 (76.51%) | |
| LVEF [%] | 61.40 ± 7.67 | 60.56 ± 7.23 | 0.63 |
| No. of diseased arteries: | 0.86 | ||
| 1 | 6 (30.00%) | 55 (36.91%) | |
| 2 | 10 (50.00%) | 68 (45.64%) | |
| 3 | 4 (20.00%) | 26 (17.45%) | |
Values are expressed as mean ± standard deviation or number (%); BMI — body mass index; CAD — coronary artery disease; MI — myocardial infarction; LVEF — left ventricular ejection fraction; PCI — percutaneous coronary intervention; VOCE — vessel-oriented composite endpoint