Figure 2. FISH on interphase nuclei with the t(8;14) and MYC break apart probes. The left upper corner demonstrates a normal FISH pattern (left) for the t(8:14) with RRGGAA. Red = MYC, Green = IGH and aqua (A) is the chromosome 8 centromere. The right upper corner is the abnormal dual fusion signal pattern representing a t(8;14). The lower panels show a normal MYC break apart probe pattern (fusion/fusion signal pattern) on the left and a rearrangement pattern RGF on the right.
