Table 2. Comparison between perioperative outcomes of RLR vs. LLR for huge (≥10 cm) tumors.
| Perioperative outcomes | Unmatched cohort | 1:3 propensity-score matching | ||||||
|---|---|---|---|---|---|---|---|---|
| Overall (n=799) | RLR (n=100) | LLR (n=699) | P value | RLR (n=73) | LLR (n=219) | P value | ||
| Median operating time [IQR], min | 270 [190–346] | 236 [176–337] | 270 [193–349] | 0.256 | 242 [197–359] | 290 [210–360] | 0.286 | |
| Median blood loss [IQR], mL | 300 [150–300] | 200 [100–500] | 300 [150–500] | 0.018 | 200 [100–500] | 300 [110–500] | 0.694 | |
| Blood loss (categories), n/n (%), mL | 0.720 | 0.511 | ||||||
| <500 | 536/742 (72.2) | 73/99 (73.7) | 463/643 (72.0) | 50/72 (69.4) | 149/204 (73.0) | |||
| ≥500 | 206/742 (27.8) | 26/99 (26.3) | 180/643 (28.0) | 22/72 (30.6) | 55/204 (27.0) | |||
| Intraoperative blood transfusion, n/n (%) | 140/797 (17.6) | 15/100 (15.0) | 125/697 (17.9) | 0.471 | 14/73 (19.2) | 37/219 (16.9) | 0.652 | |
| Pringle maneuver applied, n/n (%) | 424/769 (55.1) | 56/100 (56.0) | 368/669 (55.0) | 0.852 | 40/73 (54.8) | 131/212 (61.8) | 0.264 | |
| Median Pringle duration when applied [IQR], min | 40 [24–60] | 40 [20–60] | 40 [24–60] | 0.738 | 45 [26–60] | 45 [30–61] | 0.745 | |
| Open conversion, n (%) | 105 (13.1) | 8 (8.0) | 97 (13.9) | 0.104 | 6/73 (8.2) | 24/219 (11.0) | 0.519 | |
| Median postoperative stay [IQR], days | 6 [4–8] | 6 [4–8] | 6 [4–8] | 0.505 | 6 [4–9] | 6 [4–7] | 0.435 | |
| 30-day readmission, n/n (%) | 40/789 (5.1) | 3/100 (3.0) | 37/689 (5.4) | 0.313 | 2/73 (2.7) | 17/217 (7.8) | 0.133 | |
| Postoperative morbidity, n (%) | 190 (23.8) | 26 (26.0%) | 164 (23.5) | 0.577 | 21/73 (28.8) | 48/219 (21.9) | 0.221 | |
| Major morbidity (Clavien-Dindo grade >2), n (%) | 72 (9.0) | 4 (4.0) | 68 (9.7) | 0.061 | 3/73 (4.1) | 21/219 (9.6) | 0.152 | |
| Reoperation, n (%) | 17 (2.1) | 0 (0.0) | 17 (2.4) | 0.115 | 0/73 (0.0) | 3/219 (1.4) | 0.576 | |
| In-hospital mortality, n (%) | 11 (1.4) | 0 (0.0) | 11 (1.6) | 0.207 | 0/73 (0.0) | 4/219 (1.8) | 0.575 | |
| 90-day mortality, n (%) | 16 (2.0) | 0 (0.0) | 16 (2.3) | 0.126 | 0/73 (0.0) | 6/219 (2.7) | 0.342 | |
| Close/involved margins (≤1 mm) for malignancies, n/n (%) | 88/557 (15.8) | 9/59 (15.3) | 79/498 (15.9) | 0.935 | 7/41 (17.1) | 31/139 (22.3) | 0.654 | |
RLR, robotic liver resection; LLR, laparoscopic liver resection; IQR, interquartile range.