Table 1.

Baseline characteristics of the primary (TCGA) and secondary (TMA) HNSCC cohort

	Primary dataset (TCGA)		Secondary dataset (TMA)
	Total (n = 510)	Percent (%)	Total (n = 115)	Percent (%)
Gender
Female	132	26	27	23
Male	378	74	88	77
Age
< 60	231	45	62	54
≥ 60	279	55	53	46
Primary
Oral cavity	307	60	31	27
Oropharynx	79	15	52	45
Hypopharynx	10	2	21	18
Larynx	114	22	11	10
HPV
Negative	413	81	88	77
Positive	76	15	25	22
x	21	4	2	2
T stage
1	34	7	21	18
2	148	29	62	54
3	133	26	20	17
4	180	35	12	10
x	15	3	0	0
N stage
0	237	46	24	21
1	81	16	29	25
2	162	32	62	54
3	9	2	0	0
x	21	4	0	0
M stage
0	480	94	80	70
1	6	1	0	0
x	24	5	35	30
Staging
I	20	4	2	2
II	94	18	16	14
III	103	20	29	25
IV	280	55	68	59
x	13	3	0	0
Smoker
Never/ex	323	63	51	44
Active	173	34	64	56
x	14	3	0	0
Radiotherapy
No	86	17	0	0
Adjuvant	189	37	115	100
Primary	18	4	0	0
Neoadjuvant	6	1	0	0
x	211	41	0	0
Pharmaceutical therapy
No	129	25	96	83
Adjuvant	113	22	19	17
Primary	4	1	0	0
Neoadjuvant	8	2	0	0
x	256	50	0	0