Table 2.

Univariable and multivariable analysis of overall survival (OS) and disease-free survival (DFS) and PSMD14 mRNA expression, copy number variation (CNV) or protein expression

	Univariable			Multivariable
	HR	95% CI	p value	HR	95% CI	p value
Overall survival
TCGA
PSMD14 mRNA high vs. low	1.41	1.07–1.85	0.014	1.24	0.93–1.65	0.135
PSMD14 mRNA z-score	1.19	1.07–1.32	0.001	1.12	1.00–1.25	0.055
PSMD14 CNV high vs. low	1.09	0.83–1.43	0.539	0.94	0.71–1.26	0.685
PSMD14 CNV z-score	1.66	0.64–4.34	0.297	0.98	0.37–2.64	0.974
TMA
PSMD14 protein high vs. low	1.66	0.96–2.86	0.070	1.39	0.96–2.86	0.259
PSMD14 protein score	1.00	1.00–1.01	0.467	1.00	1.00–1.01	0.957
Disease-free survival
TCGA
PSMD14 mRNA high vs. low	1.36	1.02–1.8	0.033	1.28	0.95–1.72	0.105
PSMD14 mRNA z-score	1.16	1.04–1.29	0.007	1.12	0.99–1.25	0.069
PSMD14 CNV high vs. low	1.04	0.79–1.38	0.771	1.00	0.74–1.35	0.999
PSMD14 CNV z-score	0.94	0.34–2.62	0.905	0.69	0.24–1.98	0.496
TMA
PSMD14 protein high vs. low	1.25	0.66–2.37	0.500	1.07	0.55–2.06	0.845
PSMD14 protein score	1.01	1.00–1.02	0.263	1.00	0.99–1.01	0.542

A p value below 0.05 was considered significant (bold)

HR hazard ratio, CI confidence interval