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. 2023 Feb 18;270(5):2765–2775. doi: 10.1007/s00415-023-11615-3

Table 2.

NMSS, PDSS, and PDQ-8 scores assessed via questionnaires according to duration of LCIG treatment

Measure Time between LCIG initiation and patient visit
1–2 years
n = 156
2–3 years
n = 80
3–4 years
n = 61
4–5 years
n = 30
 > 5 years
n = 60
n Mean ± SD n Mean ± SD n Mean ± SD n Mean ± SD n Mean ± SD
NMSS total score 155 55.3 ± 43.8 79 52.6 ± 38.3 61 65.7 ± 46.2 29 62.9 ± 43.4 59 68.9 ± 37.4
PDSS-2 total score 148 19.7 ± 10.6 74 20.2 ± 10.8 59 21.9 ± 10.4 26 18.9 ± 9.1 56 22.0 ± 11.9
PDQ-8 summary index 154 36.5 ± 19.0 79 38.9 ± 18.5 60 43.9 ± 15.6 30 40.6 ± 14.3 59 46.3 ± 16.5

LCIG levodopa–carbidopa intestinal gel, NMSS Non-Motor Symptoms Scale, PDSS-2 Parkinson’s Disease Sleep Scale, PDQ Parkinson’s Disease Questionnaire, SD standard deviation