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. 2023 Apr 25;14:2385. doi: 10.1038/s41467-023-37996-7

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Fraction of cases diagnosed with one of 18 autoimmune conditions above a probability threshold on a base-10 logarithmic scale versus the fraction of individuals that are tested for autoantibodies at the equivalent probability threshold. The dashed line marks the fraction of tested individuals above each probability threshold. The gray point indicates the mean across all autoimmune conditions. The columns of points represent values at different probability thresholds decreasing from left (≥0.9) to right (≥0.1) by increments of 0.1; the most lenient threshold (≥0.1) at the farthest right column of points yields the greatest fraction of individuals with autoimmune conditions detected by the model and the greatest fraction of the population tested. b Prevalence of autoimmune conditions on a base-10 logarithmic scale in different strata of probabilities increasing from 0 to 0.1 [0, 0.1) through 1.