Table 3.
Predictive performance of FDG PET parameters for determining EGFR mutation status.
| FDG PET parameter | AUC (95% CI) | Sensitivity | Specificity | Accuracy |
|---|---|---|---|---|
| Correlation | 0.753 (0.638–0.868) | 0.659 | 0.773 | 0.697 |
| GLNUr | 0.682 (0.552–0.812) | 0.545 | 0.773 | 0.621 |
| RLNU | 0.713 (0.583–0.843) | 0.705 | 0.727 | 0.712 |
| Coarseness | 0.733 (0.608–0.859) | 0.727 | 0.659 | 0.682 |
| GLNUz | 0.662 (0.530–0.795) | 0.727 | 0.591 | 0.682 |
EGFR epidermal growth factor receptor, FDG 18F-fluorodeoxyglucose, PET positron emission tomography, AUC area under the curve, CI confidence interval, GLNUr gray-level non-uniformity for run, RLNU run length nonuniformity, GLNUz gray-level non-uniformity for zone.