Table 2.

Amount of dietary sodium bisulfite administered to rats over one year and its adverse effects (data from Fitzhugh et al., 1946) [94].

Amount of sodium bisulfite	Negative effect
0.5–2%	Damage to the nervous system, reproductive organs, bone tissue, kidneys and other internal organs
Doses lesser than 0.25%	They do not cause any pathological symptoms except diarrhea at levels above 0.1%