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. 2023 Apr 13;9(4):e15452. doi: 10.1016/j.heliyon.2023.e15452

Table 2.

Amount of dietary sodium bisulfite administered to rats over one year and its adverse effects (data from Fitzhugh et al., 1946) [94].

Amount of sodium bisulfite Negative effect
0.5–2% Damage to the nervous system, reproductive organs, bone tissue, kidneys and other internal organs
Doses lesser than 0.25% They do not cause any pathological symptoms except diarrhea at levels above 0.1%