Table 3.
Correlations between mannan-binding lectin (MBL) level and clinical/laboratory parameters in 4 groups considered: Control individuals (n=21), patients with hypopituitarism (n=42), patients with other pituitary diseases (n=57), and the whole group of individuals (n=120).
| MBL [ng/mL] r; p-value; n |
||||
|---|---|---|---|---|
| Control individuals (n=21) | Patients with hypopituitarism (n=42) | Patients with other pituitary diseases (n=57) | The whole group of individuals (n=120) | |
| Age [years] | 0.0149 p=0.949 n=21 |
-0.1050 p=0.512 n=42 |
-0.0404 p=0.765 n=57 |
-0.115 p=0.213 n=120 |
| Body mass [kg] | -0.0740 p=0.770 n=18 |
0.1010 p=0.576 n=33 |
-0.0142 p=0.922 n=50 |
-0.0192 p=0.849 n=101 |
| Height [cm] | 0.305 p=0.219 n=18 |
-0.297 p=0.0932 n=33 |
-0.0505 p=0.728 n=50 |
-0.0271 p=0.788 n=101 |
| BMI [kg/m2] | -0.163 p=0.519 n=18 |
0.0802 p=0.657 n=33 |
0.0121 p=0.934 n=50 |
-0.0381 p=0.706 n=101 |
| ACTH [pg/mL] | -0.142 p=0.599 n=16 |
-0.0887 p=0.618 n=34 |
-0.124 p=0.375 n=53 |
-0.0373 p=0.709 n=103 |
| LH [IU/L] | 0.0287 p=0.904 n=20 |
0.0260 p=0.880 n=36 |
0.102 p=0.467 n=53 |
0.121 p=0.207 n=110 |
| FSH [IU/L] | -0.0815 p=0.733 n=20 |
0.0036 p=0.983 n=36 |
-0.0922 p=0.503 n=55 |
-0.0159 p=0.869 n=111 |
| Prl [ng/mL] | 0.161 p=0.485 n=21 |
-0.0805 p=0.631 n=38 |
-0.0174 p=0.902 n=53 |
-0.0821 p=0.390 n=112 |
| IGF-I [ng/mL] | 0.220 p=0.381 n=18 |
0.4410 p=0.0049 n=40 |
0.429 p=0.002 n=51 |
0.434 p<0.001 n=108 |
| Cortisol [µg/L] | 0.120 p=0.614 n=20 |
0.0788 p=0.620 n=40 |
-0.173 p=0.203 n=56 |
0.141 p=0.127 n=116 |
| TSH [mIU/L] | 0.132 p=0.569 n=21 |
0.1630 p=0.320 n=39 |
-0.0464 p=0.732 n=57 |
0.144 p=0.122 n=117 |
| FT3 [pg/mL] | 0.122 p=0.599 n=21 |
0.2920 p=0.0639 n=42 |
0.149 p=0.268 n=57 |
0.294 p=0.0012 n=120 |
| FT4 [ng/L] | 0.223 p=0.332 n=21 |
-0.190 p=0.235 n=42 |
-0.133 p=0.324 n=57 |
-0.0562 p=0.543 n=120 |
| TPOAb [IU/mL] | 0.190 p=0.450 n=18 |
-0.200 p=0.317 n=27 |
-0.193 p=0.234 n=40 |
-0.0305 p=0.782 n=85 |
| TgAb [IU/mL] | 0.560 p=0.0156 n=18 |
-0.0758 p=0.707 n=27 |
-0.160 p=0.332 n=39 |
-0.0487 p=0.660 n=84 |
| TSHRAb [IU/L | -0.289 p=0.246 n=18 |
0.1960 p=0.337 n=26 |
0.202 p=0.217 n=39 |
0.0581 p=0.602 n=83 |
| TChol [mg/L] | -0.209 p=0.363 n=21 |
-0.0858 p=0.594 n=42 |
0.135 p=0.316 n=57 |
-0.0441 p=0.634 n=120 |
| HDLC [mg/L] | -0.0313 p=0.893 n=21 |
-0.2720 p=0.0854 n=42 |
0.0268 p=0.843 n=57 |
-0.0768 p=0.407 n=120 |
| LDLC [mg/L] | -0.191 p=0.408 n=21 |
-0.0236 p=0.884 n=42 |
0.132 p=0.326 n=57 |
0.00642 p=0.945 n=120 |
| HDLC/TChol | -0.0077 p=0.973 n=21 |
-0.2060 p=0.196 n=42 |
-0.138 p=0.312 n=56 |
-0.111 p=0.229 n=118 |
| TGs [mg/L] | -0.143 p=0.535 n=21 |
-0.1680 p=0.292 n=42 |
-0.160 p=0.332 n=39 |
-0.0309 p=0.739 n=120 |
| Glucose [mg/L] | -0.00914 p=0.694 n=21 |
0.3670 p=0.0182 n=42 |
0.207 p=0.122 n=57 |
0.177 p=0.0537 n=120 |
| RBC [1012/L] | 0.425 p=0.054 n=21 |
-0.1550 p=0.332 n=42 |
0.248 p=0.0633 n=57 |
0.204 p=0.0264 n=119 |
| Hgb [g/L] | 0.575 p=0.006 n=21 |
-0.0836 p=0.603 n=42 |
0.203 p=0.130 n=57 |
0.0793 p=0.391 n=120 |
| WBC [109/L] | -0.259 p=0.257 n=21 |
-0.2860 p=0.0698 n=42 |
0.0616 p=0.649 n=57 |
-0.124 p=0.179 n=120 |
| HCT [vol%] | 0.500 p=0.0209 n=21 |
-0.0961 p=0.550 n=42 |
0.263 p=0.0481 n=57 |
0.259 p=0.004 n=120 |
| Platelets [109/L] | -0.315 p= 0.165 n=21 |
-0.2920 p= 0.0638 n=42 |
-0.0641 p=0.636 n=57 |
-0.149 p=0.107 n=120 |
|
Neutrophils
[109/L] |
-0.255 p= 0.264 n=21 |
-0.2480 p= 0.118 n=42 |
0.0788 p=0.560 n=57 |
-0.0564 p=0.542 n=120 |
|
Lymphocytes
[109/L] |
-0.155 p= 0.502 n=21 |
-0.0877 p= 0.586 n=42 |
0.0137 p=0.919 n=57 |
-0.113 p=0.222 n=120 |
|
Eosinophils
[109/L] |
0.183 p= 0.426 n=21 |
-0.0633 p= 0.694 n=42 |
0.0377 p=0.780 n=57 |
-0.0293 p=0.751 n=120 |
|
Basophils
[109/L] |
-0.0394 p= 0.865 n=21 |
-0.1180 p= 0.462 n=42 |
-0.00193 p=0.989 n=57 |
-0.0893 p=0.334 n=120 |
|
Monocytes
[109/L] |
-0.0722 p=0.756 n=21 |
-0.0812 p=0.614 n=42 |
0.104 p=0.440 n=57 |
-0.0214 p=0.818 n=120 |
| ASPAT [U/L] | 0.0158 p= 0.946 n=21 |
-0.0176 p= 0.914 n=40 |
-0.113 p=0.402 n=57 |
-0.0302 p=0.746 n=118 |
| ALAT [U/L] | -0.0484 p= 0.840 n=20 |
0.0336 p= 0.839 n=39 |
-0.129 p=0.342 n=56 |
-0.0437 p=0.643 n=115 |
| Bilirubin [mg/L] | 0.196 p= 0.451 n=17 |
0.3960 p= 0.0154 n=37 |
-0.0748 p=0.594 n=53 |
0.129 p=0.184 n=107 |
| Na [mmol/L] | 0.411 p= 0.064 n=21 |
0.0700 p= 0.664 n=42 |
-0.0952 p=0.481 n=57 |
0.0481 p=0.603 n=120 |
| K [mmol/L] | 0.363 p=0.106 n=21 |
-0.0645 p=0.689 n=42 |
-0.268 p=0.044 n=57 |
-0.070 p=0.449 n=120 |
| Cl [mmol/L] | 0.290 p=0.203 n=21 |
-0.0422 p=0.796 n=41 |
0.0192 p=0.887 n=57 |
0.0898 p=0.334 n=118 |
| Ca [mmol/L] | 0.158 p=0.518 n=19 |
-0.2630 p=0.127 n=35 |
-0.182 p=0.207 n=50 |
-0.121 p=0.220 n=104 |
| Urea [mg/L] | 0.114 p=0.673 n=16 |
-0.1900 p=0.254 n=38 |
0.0355 p=0.809 n=49 |
-0.0304 p=0.761 n=103 |
| Creatinine [mg/L] | 0.378 p=0.100 n=20 |
-0.1970 p=0.217 n=42 |
0.0394 p=0.773 n=56 |
-0.0272 p=0.771 n=117 |
| GFR [mL/(min×1.72 m²)] | -0.216 p=0.360 n=20 |
0.2320 p=0.144 n=42 |
0.107 p=0.431 n=56 |
0.131 p=0.159 n=118 |
| Vit D [ng/mL] | 0.335 p=0.204 n=16 |
-0.1410 p=0.440 n=32 |
-0.124 p=0.453 n=39 |
-0.0579 p=0.597 n=86 |
| PTH [pg/mL] | -0.208 p=0.440 n=16 |
-0.1540 p=0.383 n=34 |
-0.152 p=0.324 n=44 |
-0.124 p=0.232 n=94 |
Statistical evaluation was performed by the Pearson’s correlation test. r - Pearson's correlation coefficient. Statistical significance was determined at the level of p<0.05. Statistically significant differences are shaded.