Table 5.

Univariate and multivariate logistic regression analyses of hypopituitarism determinants (linear variables) performed in the following groups: Control plus patients with hypopituitarism (n=21+42) (above), and the whole group of individuals (n=120) (below).

Variable	Control plus patients with hypopituitarism (n=21+42)
	Univariate regression			Multivariate regression
	OR	95%Cl	p	OR	95%Cl	p
Age [years]	1.042	1.01-1.08	0.017	0.922	0.62-1.38	0.693
MBL [ng/mL]	0.999	0.99-1.00	0.004	0.997	0.99-1.01	0.519
TSH [mIU/L]	0.455	0.28-0.75	0.002	0.164	0.01-26.72	0.487
FT3 [pg/mL]	0.043	0.01-0.23	<0.001	<0.001	1.53-3.09	0.541
TChol [mg/L]	1.013	1.00-1.03	0.049	1.110	0.79-1.55	0.541
LH [IU/L]	0.878	0.79-0.96	0.007	0.895	0.63-1.26	0.528
ACTH [pg/mL]	0.970	0.94-0.99	0.045	0.856	0.63-1.15	0.308
IGF-I [ng/mL]	0.994	0.98-1.00	0.041	1.020	0.97-1.07	0.441
Lymphocytes [109/L]	1.877	1.01-3.48	0.046	17.272	0.04-7195.24	0.355
Variable	Whole group of individuals (n=120)
	Univariate regression			Multivariate regression
	OR	95%Cl	p	OR	95%Cl	p
Age [years]	1.023	1.00-1.04	0.046	1.031	0.98-1.08	0.209
MBL [ng/mL]	1.001	0.99-1.00	0.005	1.001	0.99-1.00	0.119
TSH [mIU/L]	0.558	0.38-0.81	0.002	0.780	0.45-1.35	0.377
FT3 [pg/mL]	0.186	0.075-0.46	<0.001	0.640	0.13-3.07	0.577
TChol [mg/L]	1.009	1.00-1.018	0.045	1.018	1.00-1.03	0.019
LH [IU/L]	0.849	0.78-0.93	<0.001	0.841	0.68-1.04	0.115
FSH [IU/L]	0.949	0.91-0.987	0.008	1.003	0.91-1.10	0.952
ACTH [pg/mL]	0.970	0.94-0.99	0.004	0.982	0.95-1.01	0.241
IGF-I [ng/mL]	0.992	0.99-1.00	0.004	1.002	0.99-1.01	0.483
Lymphocytes [109/L]	1.732	1.16-2.58	0.007	1.221	0.62-2.41	0.564
Creatinine [mg/L]	9.108	1.32-62.93	0.025	3.227	0.17-59.98	0.432

Only statistically significant determinants are presented in the univariate analysis. Statistical significance was determined at the level of p<0.05. Statistically significant differences are shaded.