Fig. 2.

Serum 25-hydroxyvitamin D levels by treatment arm (panel A); Kaplan Meier plot of proportion with confirmed relapse by treatment arm (panel B). Panel A depicts a spaghetti plot of individual participant serum 25(OH)D levels at each time point from baseline to week 96 for low dose (dark blue lines) compared to high dose (orange lines) vitamin D treatment arms with overlaid loess curves of mean levels over time. Panel B shows the results of the Kaplan Meier survival analysis (risk of confirmed relapse at 96 weeks) for low dose (dark blue line) compared to high dose (orange line) vitamin D treatment arms (p = 0.60 by log rank test); the hazard ratio (95% confidence interval) from the Cox proportional hazard model is 1.17 (0.67–2.05); p = 0.57.