Table 1. FDA approved submucosal lifting agents.
| Compound and company | Active ingredient | Contrast agent | FDA approved date |
|---|---|---|---|
| SIC-8000 (Eleview) (Cosmo Pharmaceuticals) | Poloxamer 188 | Methylene blue | September 2015 |
| Polyoxyl-15-hydroxystearate | |||
| ORISE gel (Boston Scientific) | Gellan gum | FD&C blue No. 1 | September 2018 |
| Polysaccharide | |||
| BlueBoost (Micro-Tech Endoscopy) | Sodium hyaluronate | Methylene blue | June 2021 |
| EverLift (Laborie Medical Technologies) | Cellulose | Methylene blue | July 2020 |
| EndoClot SIS (Olympus) | Absorbable starch polymers | No contrast added | April 2020 |
| LiftUp (Ovesco) | Poloxamers (thermo-sensitive gel formulation) | Methylene blue | August 2022 |
FDA, Food and Drug Administration.