| ORISE visible in resection specimen |
Pathologist mistakes material for mucin or amyloid |
| ORISE injected to test lifting before referral to resectionist |
Submucosa tough at time of endoscopic resection; foreign material interferes with further lifting; mimics submucosal invasion during transection |
| ORISE used as endoscopic mucosal resection lifting agent leading to mass effect in submucosa and muscularis propria that is visible at endoscopic follow-up or during surgical resection |
Endoscopist believes mass effect is tumor in wall and refers patient to surgery |
| Surgeon sees mass effect and believes cancer present |
| Mass effect interferes with resection, anastomosis creation |
