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. 2023 Apr 25;329(16):1401–1402. doi: 10.1001/jama.2023.2296

Table. Information Provided on the Label Compared With Quantity Detected of Melatonin and CBD in Analyzed Samples of Melatonin Gummies.

Brand code Label claims Expiration date Labeled quantity of ingredients per serving size No. of other ingredientsa Label maximum daily servings, No. of gummies Measured ingredients per serving size (SD), mg Measured vs labeled ingredients per serving size, %
A Circadian rhythm support 06/2024 Melatonin, 3 mg
CBD, 10 mg
2 1 Melatonin: 3.6 (0.7)
CBD: 10.6 (0.5)
Melatonin: 120
CBD: 106
B Heartburn relief plus sleep support 01/2024 Melatonin, 3 mg 0 2 4.8 (0.3) 160
C Occasional sleeplessness 09/2023 Melatonin, 5 mg 0 2 6.1 (0.2) 122
D Rest and rejuvenate 03/2023 Melatonin, 5 mg 1 2 3.7 (0.4) 74
E Night calm 02/2024 Melatonin, 3 mg 3 2 4.5 (0.3) 150
F Sleep 08/2024 Melatonin, 5 mg
CBD, 15 mg
0 2 Melatonin: 6.6 (0.2)
CBD: 15.8 (0.1)
Melatonin: 132
CBD: 105
G Sleep 08/2024 Melatonin, 5 mg
CBD, 15 mg
0 2 Melatonin: 7.2 (0.3)
CBD: 17.7 (1.0)
Melatonin: 144
CBD: 118
H Sleep 05/2023 Melatonin, 5 mg
CBD, 15 mg
0 2 Melatonin: 4.7 (0.1)
CBD: 16.1 (0.2)
Melatonin: 94
CBD: 107
I Sleep support 08/2024 Melatonin, 5 mg
CBD, 30 mg
0 2 Melatonin: ND
CBD: 31.3 (1.1)
Melatonin: ND
CBD: 104
J No claim 06/2023 Melatonin, 5 mg 0 2 6.0 (0.1) 120
K No claim 12/2023 Melatonin, 3 mg 1 2 4.6 (0.3) 153
L Healthy sleep cycle support 02/2024 Melatonin, 5 mg 0 2 5.9 (0.3) 118
M Supports healthy sleep 11/2023 Melatonin, 5 mg 0 1 7.3 (0.1) 146
N Supports healthy sleep 02/2024 Melatonin, 10 mg 0 2 13.1 (0.1) 131
O No claim 10/2023 Melatonin, 5 mg 0 2 5.4 (0.4) 108
P No claim 09/2023 Melatonin, 3 mg 1 2 5.1 (0.8) 170
Q Rest and restore muscles 08/2023 Melatonin, 3 mg 2 2 4.0 (0.3) 133
R No claim 02/2024 Melatonin, 3 mg 2 2 3.8 (0.1) 126
S Sleep plus immune 09/2023 Melatonin, 3 mg 5 2 10.4 (0.4) 347
T No claim 05/2024 Melatonin, 2.5 mg 0 1 2.9 (0.3) 116
U No claim 07/2023 Melatonin, 1.0 mg 0 1 1.3 (0.4) 130
V Sleep support, wake-up 10/2023 Melatonin, 10 mg 3 2 9.2 (0.3) 92
W Supports restful sleep 09/2023 Melatonin, 5 mg 0 2 5.8 (0.6) 116
X No claim 09/2023 Melatonin, 5 mg 0 2 5.7 (1.3) 114
Y Sleep health 07/2023 Melatonin, 3 mg 1 2 3.7 (0.2) 123

Abbreviations: CBD, cannabidiol; ND, not detected where limit of detection is 100 ng/mL.

a

Other ingredients declared included extracts of lemon balm, passionflower, tart cherry fruit, magnolia, Griffonia simplicifolia, wild blueberry, black elderberry, and chamomile flower as well as collagen, L-theanine, vitamin C, and vitamin D.