Table 1.
Clinical data from patients with Crohn’s disease and healthy subjects
|
|
Group Ia (n = 50)
|
Group Ib (n = 16)
|
Group II (n = 39)
|
Control (n = 40)
|
| General characteristics | ||||
| Male:Female (ratio) | 29:21 (1.38) | 8:8 (1) | 22:17 (1.29) | 15:25 (0.6) |
| Age (years), mean ± SD | 13 ± 2.9 | 15 ± 2.8 | 12.5 ± 4.3 | 11 ± 4.1 |
| BMI (kg/m2), mean ± SD | 17.0 ± 3.1 | 18.1 ± 2.7 | 18.1 ± 3.2 | 18.3 ± 3.8 |
| PCDAI, mean ± SD | 34.4 ± 12.7 | 38.2 ± 18.6 | 4.1 ± 3.9 | N/A |
| Disease distribution by Paris classification (number of patients) | ||||
| A1a | 4 | 2 | 7 | |
| A1b | 46 | 14 | 30 | |
| A2 | 0 | 2 | 2 | |
| L1 | 2 | 1 | 2 | |
| L2 | 6 | 2 | 7 | |
| L3 | 16 | 4 | 12 | |
| L4aL1 | 8 | 2 | 6 | |
| L4aL2 | 8 | 3 | 5 | |
| L4aL3 | 10 | 4 | 7 | |
| B1 | 39 | 11 | 27 | |
| B2 | 11 | 5 | 12 |
Group Ia: Active/newly diagnosed Crohn's disease (CD); Group Ib: Active/previously diagnosed and treated CD; Group II: Non-active CD; control: Healthy subjects; Paris classification: Age: A1a (0–10 yr), A1b (10–17 yr), A2 (17–40 yr); Location: L1 (distal 1/3 ileum and/or limited cecal disease), L2 (colonic), L3 (ileocolonic), L4a (upper disease proximal to ligament of Treitz), L4b (upper disease distal to ligament of Treitz and proximal to distal 1/3 ileum); Behaviour: B1 (non-structuring non-penetrating), B2 (structuring), B3 (penetrating), B2B3 (both penetrating and structuring disease either at the same or different times); BMI: Body mass index; PCDAI: Pediatric Crohn’s disease activity index; N/A: Not applicable.