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. 2023 Apr 14;29(14):2064–2077. doi: 10.3748/wjg.v29.i14.2064

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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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The origin and ancestral relationship of severe acute respiratory syndrome coronavirus 2 with other related viruses. Whole genome sequencing revealed that severe acute respiratory syndrome coronavirus 2 virus was most closely related to the CoV RaTG13 virus. The variant strains of coronavirus and their biogeographical distribution are illustrated. MERS-CoV: Middle East respiratory syndrome coronavirus; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; R. affinis RaTG13: SARS-like coronaviruses: Bat-SLCoVZX.